RNA Details
Disease Name
heart failure
Tissue
heart
RNA Symbol
Kcnq1ot1
RNA ID
RNA Type
lncrna
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
qRT-PCR;
Target
FUS
Pathway
NA
PubMed ID
Title
LncRNA KCNQ1OT1 contributes to cardiomyocyte apoptosis by targeting FUS in heart failure
Year
2020
Function
"Kcnq1ot1 ovexpression improved myocardial histopathological changes, reduced myocardial fibrosis areas, down-regulated FUS expression, and inhibited cell apoptosis of heart failure(HF) mice."